type i b lymphoma cell line akata (ATCC)
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Type I B Lymphoma Cell Line Akata, supplied by ATCC, used in various techniques. Bioz Stars score: 94/100, based on 478 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 94 stars, based on 478 article reviews
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1) Product Images from "An allosteric inhibitor of sirtuin 2 deacetylase activity exhibits broad-spectrum antiviral activity"
Article Title: An allosteric inhibitor of sirtuin 2 deacetylase activity exhibits broad-spectrum antiviral activity
Journal: The Journal of Clinical Investigation
doi: 10.1172/JCI158978
Figure Legend Snippet: ( A ) Akata BL cells were stimulated with 10 μg/mL anti-IgG and simultaneously treated with DMSO, 100 μM phosphonoacetic acid (PAA; positive control), or increasing concentrations of FLS-359 (1, 5, and 10 μM). Surface expression of the viral late gene gp350 was measured at 24 hours after induction by flow cytometry. ( B ) Dot plots reporting experiments in A , shown with mean ± SD ( n = 4). * P < 0.05, ** P < 0.01, and **** P < 0.0001. ( C ) Dot plots reporting quantitative reverse transcriptase PCR (qRT-PCR) measurement of BZLF1 (IE, immediate early), BMRF1 (E, early), and BLLF1 (L, late) gene expression suppressed by FLS-359 (10 μM) in Akata BL cells induced with anti-IgG. Mean ± SD is shown ( n =3).
Techniques Used: Positive Control, Expressing, Flow Cytometry, Reverse Transcription, Quantitative RT-PCR, Gene Expression
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